陈红星，博士，副教授，硕士生导师。
教育和工作履历：
2023年至今，华南师范大学环境学院/研究院，副教授
2017年-2023年，华南师范大学环境学院/研究院，讲师
2019年-2020年，美国杜克大学(Duke University)，访问学者
2016年-2017年，中国科学院沈阳应用生态研究所，助理研究员
2013年-2016年，中国科学院沈阳应用生态研究所，环境科学，博士
2010年-2013年，沈阳师范大学，生物化学与分子生物学，硕士
2006年-2010年，河南师范大学，生物科学，学士
开设课程：
本科生课程：《生态毒理学与实验》、《普通生物学》等。
研究生课程：《生态毒理学实验方法与技术》、《环境科学与生态学前沿》等。
研究领域：生态毒理学、环境健康、进化生物学、暴露组学。
研究方向：主要从事水生生态毒理学研究，聚焦全球环境变化背景下环境污染物的生态暴露组（Eco-exposome）、跨生态系统迁移及生态健康效应。综合运用环境化学、多组学、分子生物学、生物信息学、进化生物学及生态建模等方法，构建覆盖环境暴露-生物富集-关键分子事件-不良结局路径（AOP）-生态风险的跨尺度研究体系，系统解析污染物在多重环境胁迫下对水生生物从分子、器官、个体到种群及生态系统的作用机制。重点关注污染物在食物链和水陆生态界面的迁移转化、生物放大、跨代效应及生物适应性响应，揭示环境胁迫驱动下生物表型可塑性、环境适应与潜在进化响应的生态学机制，推动多组学驱动生态毒理学、预测生态毒理学的发展，为One Health和Planetary Health框架下的生态环境安全评价与污染精准防控提供理论基础。
科研项目和成果：
近年来主持/完成国家自然科学基金面上项目、国家自然科学基金青年基金、广东省自然科学基金面上项目、广东省普通高校青年创新人才项目、广州市基础与应用基础研究项目、华南师范大学青年教师科研培育基金等多项；作为骨干人员参与国家自然科学基金重点项目、国家重点研发计划子课题、中科院“百人计划”项目等。在Environmental Science & Technology、Journal of Hazardous Materials、Environmental International、Environmental Pollution等期刊发表学术论文80余篇，发表专利1项。担任生态环境领域多个国际著名期刊审稿人。
主持科研项目：
1. 国家自然科学基金委，面上项目，硒对卵生鱼类卵黄吸收期致畸效应通路与机制研究（42177256）
2. 国家自然科学基金委，青年基金，食物相硒拮抗镉毒性与硒镉母体共传递效应及机制的研究（41807352）
3. 广东省科学技术厅，面上项目，卵生和卵胎生鱼类对食物相硒敏感性差异及机制研究（2020A1515010508）
4. 广州市科学技术局，一般项目，新型纳米硒饲料添加剂对青鳉鱼繁殖及子代发育的影响（202201010443）
5. 广东省教育厅，普通高校青年创新人才项目（2017KQNCX050）
6. 华南师范大学，青年教师科研培育基金（17KJ18）
代表性论文列表：
1. Wu, F., Deng, Y., Wu, Q., Chen, H., Mu, J., Zhang, Y., Meng, W., Li, N., Xie, L., 2026. Heteroaggregation with microalgae masks charge-dependent accumulation but amplifies charge-dependent toxicity of nanoplastics in mussels. J. Hazard. Mater. 510, 142121.
2. Sun, J., Tu, S., Li, Z., Li, K., Zhang, Y., Huang, Q., Chen, T., Chen, H., Xie, L., Yan, B., 2026. Photochemical ROS-Driven Autocatalytic Transformation of Heavy Metal–Xanthate Complex Pollutants in Tailings Pond. Environ. Sci. Technol. 60, 12427-12438.
3. Chen, H., Tang, C., Huang, K., Zhou, W., Lou, C., Wu, F., Huang, T., Luo, Y., Xie, L., 2026. Dietary copper induces cuproptosis and disrupts the gut-gonadal axis in zebrafish (Danio rerio). Environ. Pollut. 396, 127892.
4. Zhang, Y., Huang, Q., Sun, J., Li, K., Chen, H., Chen, T., Xie, L., Li, Z., Yan, B., 2026. Unveiling the overlooked environmental risks of organic flotation reagents: Intergenerational toxicity of potassium ethylxanthate to Daphnia magna. Aquat. Toxicol. 290, 107656.
5. Xu, Y., Bo, X., Zhang, Y., Li, X., Xie, L., Yang, Y., Yu, J., Dong, W., Chen, H., 2026. Mechanism of liver injury induced by Cr6+ in zebrafish and protective effect of selenomethionine. Animals 16, 687.
6. Xie, X., Zhang, X., Li, L., Wu, F., Chen, H., 2026. Dietary selenium nanoparticle shows gender-specific effects on the reproduction of Japanese medaka. Ecotoxicology 35.
7. Wu, F., Wu, Q., Deng, Y., Lou, C., Chen, H., Luo, Y., Yan, B., Xie, L., 2026. When nanoplastics (NPs) meet algae: Heteroaggregates exacerbate bioaccumulation, immunotoxicity, and microbial dysbiosis in the green mussel (Perna viridis). J. Hazard. Mater. 501, 140694.
8. Lin, H., Luo, Y., Li, L., Wu, F., Chen, H., Xie, L., 2026. Species-specific effects and trophic transfer of selenium in a freshwater food chain. Comp. Biochem. Phys. C 305, 110504.
9. Huang, K., Yan, X., Zhou, W., Lou, C., Yan, B., Chen, T., Wu, F., Dong, W., Luo, Y., Chen, H., Xie, L., 2026. Bioaccumulation and endocrine effects of sediment-derived copper transferred from oligochaete Lumbriculus variegatus to fish Danio rerio. Aquat. Toxicol. 292, 107738.
10. Wei, X., Li, X., Zhou, W., Yan, B., Chen, T., Wu, F., Luo, Y., Mu, J., Zhang, Y.T., Chen, H., Xie, L., 2025. Why western mosquitofish (Gambusia affinis) is tolerant to Se contamination: Complex mechanistic explanations. Environ. Sci. Technol. 59, 8484-8494.
11. Huang, Z., Wei, X., Zhang, L., Chen, T., Huang, Y., Yang, Z., Zeng, W., Chen, H., Xie, L., Yan, B., 2025. Reduction of pentavalent vanadium via enhanced levels of sulfhydryl by elemental sulfur reducing bacteria from a stone coal mining region. ACS ES&T Engineering 5, 1857-1867.
12. Huang, Q., Zhang, Y., Sun, J., Li, K., Chen, H., Chen, T., Xie, L., Li, Z., Yan, B., 2025. Effects of potassium ethyl xanthate on Chlorella pyrenoidosa: Physiological, ultrastructural, and transcriptomic insights. Ecotoxicol. Environ. Saf. 307, 119427.
13. Gao, Y., Chen, H., Lian, H., Cai, X., Xie, L., Ahmed, R., Lin, X., Chen, H., Dong, W., 2025. The role of the ferroptosis pathway in the toxic mechanism of TCDD-induced liver damage in zebrafish. Comp. Biochem. Phys. C 295, 110213.
14. Chen, H., Chernick, M., Dong, W., Xie, L., Hinton, D.E., 2025. The role of chorion integrity on the bioaccumulation and toxicity of selenium nanoparticles in Japanese medaka (Oryzias latipes). Aquat. Toxicol. 278, 107170.
15. Zhou, W., Chen, J., Liu, P., Wang, F., Chen, H., 2024. Comparative effects of different metals on the Japanese medaka embryos and larvae. Ecotoxicology 33, 653-661.
16. Wang, F., Liu, P., Li, J., Xu, S., Chen, H., Xie, L., 2024. Effects of four antibiotics on the photosynthetic light reactions in the green alga Chlorella pyrenoidosa. Comp. Biochem. Phys. C 281, 109927.
17. Sun, J., Yan, B., Chen, H., Tu, S., Zhang, J., Chen, T., Huang, Q., Zhang, Y., Xie, L., 2024. Insight into the mechanisms of combined toxicity of cadmium and flotation agents in luminescent bacteria: Role of micro/nano particles. Sci. Total Environ. 940, 173588.
18. Sun, W., Liu, T., Lei, H., Wei, X., Li, L., Chen, H., Li, D., Xie, L., 2023. Evaluation of cyclophosphamide on the behavior and reproduction of Daphnia magna. ACS ES&T Water 3, 996-1006.
19. Liu, P., Li, D., Wang, F., Xie, L., Chen, H., 2023. Transfer of Se from sediments to the western mosquitofish Gambusia affinis: Tissue distribution, accumulation, and effects on the antioxidant physiology. Aquat. Toxicol. 262, 106663.
20. Tan, J., Chen, H., Chen, S., Hu, J., Wang, X., Wang, Y., Liao, S., Chen, P., Liang, C., Dai, M., Du, Q., Hou, L., 2022. The interactive effects of ethinylestradiol and progesterone on transcriptional expression of genes along the hypothalamus–pituitary–thyroid axis in embryonic zebrafish (Danio rerio). Sci. Total Environ. 805, 150371.
21. Wei, X., Li, X., Liu, H., Lei, H., Sun, W., Li, D., Dong, W., Chen, H., Xie, L., 2022. Altered life history traits and transcripts of molting-and reproduction-related genes by cadmium in Daphnia magna. Ecotoxicology 31, 735-745.
22. Qiu, S.-Q., Li, X.-P., Huang, G.-Y., Lei, D.-Q., Fang, G.-Z., Shi, W.-J., Chen, H.-X., Xie, L., Ying, G.-G., 2022. Chemical profile and toxicity of the leachates from aged plastics under simulated conditions. Journal of Cleaner Production 375, 134151.
23. Li, X., Liu, H., Li, D., Lei, H., Wei, X., Schlenk, D., Mu, J., Chen, H., Yan, B., Xie, L., 2021. Dietary Seleno-l-Methionine Causes Alterations in Neurotransmitters, Ultrastructure of the Brain, and Behaviors in Zebrafish (Danio rerio). Environ. Sci. Technol. 55, 11894-11905.
24. Liu, H., Li, X., Lei, H., Li, D., Chen, H., Schlenk, D., Yan, B., Yongju, L., Xie, L., 2021. Dietary Seleno-l-methionine Alters the Microbial Communities and Causes Damage in the Gastrointestinal Tract of Japanese Medaka Oryzias latipes. Environ. Sci. Technol. 55, 16515-16525.
25. Li, D., Chen, H., Liu, H., Schlenk, D., Mu, J., Lacorte, S., Ying, G.-G., Xie, L., 2021. Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment. Environ. Int. 153, 106543.
26. Huang, G.-Y., Shi, W.-J., Fang, G.-Z., Liang, Y.-Q., Liu, Y.-S., Liu, S.-S., Hu, L.-X., Chen, H.-X., Xie, L., Ying, G.-G., 2020. Endocrine disruption in western mosquitofish from open and closed aquatic ecosystems polluted by swine farm wastewaters. Environ. Int. 137, 105552.
27. Wang, H., Chen, H., Chernick, M., Li, D., Ying, G.-G., Yang, J., Zheng, N., Xie, L., Hinton, D.E., Dong, W., 2020. Selenomethionine exposure affects chondrogenic differentiation and bone formation in Japanese medaka (Oryzias latipes). J. Hazard. Mater. 387, 121720.
28. Luo, Y., Chen, H., Li, D., Zhan, M., Hou, L., Dong, W., Luo, Y., Xie, L., 2020. The effects of norethindrone on the ontogeny of gene expression along the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes in zebrafish (Danio rerio). Sci. Total Environ. 747, 141554.
29. Chen, H., Li, J., Yan, L., Cao, J., Li, D., Huang, G.-Y., Shi, W.-J., Dong, W., Zha, J., Ying, G.-G., Zhong, H., Wang, Z., Huang, Y., Luo, Y., Xie, L., 2020. Subchronic effects of dietary selenium yeast and selenite on growth performance and the immune and antioxidant systems in Nile tilapia Oreochromis niloticus. Fish Shellfish Immunol. 97, 283-293.
30. Chen, H., Yan, L., Zhao, J., Yang, B., Huang, G., Shi, W., Hou, L., Zha, J., Luo, Y., Mu, J., Dong, W., Ying, G.-G., Xie, L., 2019. The role of the freshwater oligochaete Limnodrilus hoffmeisteri in the distribution of Se in a water/sediment microcosm. Sci. Total Environ. 687, 1098-1106.
31. Li, D., Chen, H., Bi, R., Xie, H., Zhou, Y., Luo, Y., Xie, L., 2018. Individual and binary mixture effects of bisphenol A and lignin-derived bisphenol in Daphnia magna under chronic exposure. Chemosphere 191, 779-786.
32. Chen, H., Zeng, X., Mu, L., Hou, L., Yang, B., Zhao, J., Schlenk, D., Dong, W., Xie, L., Zhang, Q., 2018. Effects of acute and chronic exposures of fluoxetine on the Chinese fish, topmouth gudgeon Pseudorasbora parva. Ecotoxicol. Environ. Saf. 160, 104-113.
33. Chen, H., Guo, Z., Zhou, Y., Li, D., Mu, L., Klerks, P.L., Luo, Y., Xie, L., 2018. Accumulation, depuration dynamics and effects of dissolved hexavalent chromium in juvenile Japanese medaka (Oryzias latipes). Ecotoxicol. Environ. Saf. 148, 254-260.
34. Chen, H., Mu, L., Cao, J., Mu, J., Klerks, P.L., Luo, Y., Guo, Z., Xie, L., 2016. Accumulation and effects of Cr(VI) in Japanese medaka (Oryzias latipes) during chronic dissolved and dietary exposures. Aquat. Toxicol. 176, 208-216.
35. Chen, H., Cao, J., Li, L., Wu, X., Bi, R., Klerks, P.L., Xie, L., 2016. Maternal transfer and reproductive effects of Cr(VI) in Japanese medaka (Oryzias latipes) under acute and chronic exposures. Aquat. Toxicol. 171, 59-68.
更多内容请见学院网页：华南师范大学-环境学院
邮箱：hongxing.chen@m.scnu.edu.cn
欢迎生物学、生物技术、毒理学、生物化学、分子生物学、生物信息学、生态学、水产、化学等相关专业背景的优秀本科毕业生报考研究生。